Decade Advance of Isatin in Three‐component Reactions. Issue 2 (8th January 2023)

• Record Type: Journal Article
• Authors: Zhang, Shuaijie; Huang, Dayun; Wu, Jinjing; Wang, Zefeng
• Is Part Of: Asian journal of organic chemistry. Volume 12:Issue 2(2023)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2023-01-08
• Subjects: Isatin -- electrophile -- three-component reactions -- mechanism; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.202200591
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: Isatin is an important building block in organic synthesis. The electron‐deficient carbonyl in C‐3 site is similar to aldehyde. C‐3 carbonyl is also able to function as the O‐nucleophile. Devise methodologies about three‐component reactions of isatin have been reported in this decade. This review highlights these multicomponent reactions by triggered mechanisms. We hope it will promote future research in this area. Abstract : Isatin is an important building block in organic synthesis. The electron‐deficient carbonyl in C‐3 site is similar to aldehyde. C‐3 carbonyl is also able to function as the O‐nucleophile. Devise methodologies about three‐component reactions of isatin have been reported in this decade. This review highlights these multicomponent reactions by triggered mechanisms. We hope it will promote future research in this area.