Free radical scavenging synergism of fucoxanthin with lipophilic plant products. Issue 5 (4th March 2023)

• Record Type: Journal Article
• Authors: Nurcahyanti, Agustina Dwi Retno; Satriawan, Natasha; Sharopov, Farukh
• Is Part Of: Natural product research. Volume 37:Issue 5(2023)
• Page Start: 782
• Page End: 787
• Publication Date: 2023-03-04
• Subjects: synergism -- fucoxanthin -- free radical -- eugenol -- essential oils -- grapeseed oils; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2022.2084737
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Fucoxanthin demonstrates potential bioactivity, gaining greater interest with many prospective applications. The fundamental activity of fucoxanthin is antioxidant. However, some findings also report the pro-oxidant potential of carotenoids in particular concentrations and environments. In many applications, fucoxanthin requires additional materials to improve bioavailability and stability, such as lipophilic plant products (LPP). Despite much-growing evidence, little is known how fucoxanthin interacts with LPP, which is susceptible to an oxidative reaction. We hypothesised that lower concentration of fucoxanthin exerts a synergistic effect in combination with LPP. The low molecular weight of LPP may exhibit greater activity than long-chain LPP, and so it does with the concentration of unsaturated moieties. We performed free radical-scavenging assay of fucoxanthin combined with some essential oils and edible oils. Chou-Talalay theorem was employed to depict the combination effect. The current study demonstrates a staple finding and constitutes theoretical viewpoints before further fucoxanthin's utilization with LPP. Graphical Abstract: UF0001