Viscoelastic shear properties of the fresh porcine lens. Issue 3 (11th October 2006)

• Record Type: Journal Article
• Authors: Schachar, Ronald A; Chan, Roger W; Fu, Min
• Is Part Of: British journal of ophthalmology. Volume 91:Issue 3(2007)
• Page Start: 366
• Page End: 368
• Publication Date: 2006-10-11
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.2006.105965
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Aim: To determine the viscoelastic properties of the porcine lens Methods: Linear viscoelastic shear properties of the stroma of four porcine lenses were measured within 5 hours post-mortem, using sinusoidal oscillatory shear deformation. The elastic shear modulus, viscous shear modulus, dynamic viscosity, damping ratio, and phase shift of the lenses were quantified by a controlled-strain, linear simple-shear rheometer at frequencies of 10–50 Hz. Results: The mean viscoelastic properties and their standard deviations across the frequencies examined were: the elastic shear modulus, G′ = 6.2±4.0 Pa, the viscous shear modulus, G″ = 19.2±2.5 Pa, the dynamic viscosity, η′ = 0.16±0.1 Pasec, the damping ratio ζ = 4.06±1.25, and the phase shift, δ = 76°± 5.6°. Conclusions: The measured viscoelastic shear properties of the porcine lens reflect a low dynamic viscosity with a high damping ratio. The porcine lens is viscoelastic and is more viscous than elastic. The magnitude of the complex shear modulus of the porcine lens, |G*|, is similar to the shear modulus of the young human lens. Understanding these viscoelastic properties of the natural lens may provide guidance in developing a lens substitute capable of accommodation in the post cataract patient.