Electrochemical oxidative intramolecular annulation of aryl phosphine compounds: an efficient approach for synthesizing π-conjugated phosphonium salts. Issue 4 (9th February 2023)

• Record Type: Journal Article
• Authors: Zhang, Tianmei; Cai, Min; Zhao, Wenfeng; Liu, Mao; Jiang, Nan; Ge, Qingmei; Cong, Hang
• Is Part Of: Green chemistry. Volume 25:Issue 4(2023)
• Page Start: 1351
• Page End: 1355
• Publication Date: 2023-02-09
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/d2gc04569a
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A simple electrochemical oxidation cyclization strategy for the construction of polycyclic phosphonium salts skeletons from trivalent arylphosphines was established. Abstract : A practical and efficient electrochemical approach for the synthesis of π-conjugated phosphonium salts via intramolecular annulation and the construction of the C–P bond is developed. This reaction proceeded under catalyst- and adscititious oxidant-free conditions at room temperature. A series of substituted π-conjugated phosphonium salt products were obtained with good functional group tolerance and yields. A gram-scale reaction was performed to demonstrate the potential of the protocol for practical applications. Preliminary mechanistic studies indicate that free radicals are thought to be involved in this process.