Orolingual angioedema to alteplase. Identify, counsel and monitor at risk patients. (2nd September 2016)

• Record Type: Journal Article
• Authors: Timmis, Christopher; Epstein, Elliot; Salim, Mohmad
• Is Part Of: BMJ case reports. Volume 2016
• Publication Date: 2016-09-02
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2016-216133
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Orolingual angioedema (OLA) is a known complication of intravenous alteplase used to treat ischaemic stroke. The incidence may be as high as 5.1%. ACE inhibitors are thought to increase the risk of developing this potentially life-threatening complication. This case report demonstrates how we may improve in the identification of risk factors in the history; the counselling of patients appropriately; in seeking alternative therapies such as mechanical thrombectomy; and in the monitoring of patients for signs of OLA once alteplase has been given.