HPV Associated Squamous Cell Carcinoma in the Rectal Tonsil. (May 2023)

• Record Type: Journal Article
• Authors: Desai, Ketav; Baskovich, Brett; Alkhasawneh, Ahmad; Mohamed, Khaled; Omman, Reeba; Gopinath, Arun
• Is Part Of: International journal of surgical pathology. Volume 31:Number 3(2023)
• Page Start: 312
• Page End: 315
• Publication Date: 2023-05
• Subjects: rectal -- tonsil -- HPV -- squamous -- carcinoma; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/10668969221101870
• Languages: English
• ISSNs: 1066-8969

Abstract

Mucosa-associated lymphoid tissue has been reported throughout the gastrointestinal tract including rectum. Rarely, a nodular proliferation of predominantly submucosal lymphoid tissue in the rectum has been documented as rectal tonsil. Here we report a patient with HPV-associated squamous cell carcinoma of the rectal tonsil, presenting as a polyp. Previously, rare reports of HPV-associated lymphoepithelial carcinoma have been reported in the literature. We are presenting an extremely rare occurrence and emphasizing the importance of appropriate nomenclature based on the pathogenesis of the neoplasm.