Anterolateral thigh flap with a central hole for the repair of extensive oral defects in patients treated for chemotherapy-induced trismus. Issue 3 (March 2023)

• Record Type: Journal Article
• Authors: Li, R.; Meng, Z.; Zhang, Y.; He, Y.
• Is Part Of: International journal of oral & maxillofacial surgery. Volume 52:Issue 3(2023)
• Page Start: 313
• Page End: 317
• Publication Date: 2023-03
• Subjects: Drug therapy -- Trismus -- Free tissue flaps -- Reconstructive surgical procedures -- Microsurgery; Mouth -- Surgery -- Periodicals; Maxilla -- Surgery -- Periodicals; Dentistry -- Periodicals; Dentistry, Operative; Oral Surgical Procedures; Surgery, Oral; Dentistry; Maxilla -- Surgery; Mouth -- Surgery; Electronic journals; Periodicals; 617.52059
• DOI: 10.1016/j.ijom.2022.07.012
• Languages: English
• ISSNs: 0901-5027

Abstract

Abstract: Trismus is a rare complication of chemotherapy. The usefulness of a modified anterolateral thigh (ALT) flap for the repair of extensive oral defects in patients treated for chemotherapy-induced trismus was evaluated. Between 2019 and 2021, three patients with chemotherapy-induced trismus underwent scar excision. A thinned ALT flap with a central hole was designed to repair the resultant oral mucosal defects. The patients were followed up for a mean 9.3 months (range 4–18 months). The mean pre- and intraoperative maximum inter-incisal opening (MIO) was 0.7 cm (range 0–2.0 cm) and 3.6 cm (range 3.4–3.7 cm), respectively, indicating a significant operative effect. MIO at the latest follow-up was 2.4 cm (range 1.5–3.5 cm). All of the flaps survived without complications. All patients achieved a good diet and were satisfied with the aesthetics. Thorough excision of the perioral scar and restoration with a modified ALT flap achieved satisfactory mouth opening and cosmetic effects in patients with chemotherapy-induced trismus.