The troubled puberty of malaria parasites. Issue 3 (March 2023)

• Record Type: Journal Article
• Authors: Gockel, Jonas; Voss, Till S.; Bártfai, Richárd
• Is Part Of: Trends in parasitology. Volume 39:Issue 3(2023)
• Page Start: 155
• Page End: 157
• Publication Date: 2023-03
• Subjects: malaria -- Plasmodium -- gametocytes -- transmission -- sex determination -- sexual differentiation; Parasitology -- Periodicals; Parasitology -- Periodicals; Biology -- Periodicals; Parasitology; Biology; Parasitologie -- Périodiques; Online resources; 571.999
• DOI: 10.1016/j.pt.2023.01.006
• Languages: English
• ISSNs: 1471-4922

Abstract

Abstract: Sexual differentiation of malaria parasites is essential for transmission, yet the underlying mechanisms are poorly understood. Russell et al . elegantly combined a loss-of-function screen with single-cell RNA-sequencing to identify key factors in this process. Gomes et al . further characterized one of them, MD1, as a regulator contributing to male fate determination.