Organs-on-chips: a decade of innovation. Issue 3 (March 2023)

• Record Type: Journal Article
• Authors: Strelez, Carly; Jiang, Hannah Y.; Mumenthaler, Shannon M.
• Is Part Of: Trends in biotechnology. Volume 41:Issue 3(2023)
• Page Start: 278
• Page End: 280
• Publication Date: 2023-03
• Subjects: microphysiological systems -- organ-on-a-chip -- drug discovery; Biotechnology -- Periodicals; Biochemical engineering -- Periodicals; Genetic engineering -- Periodicals; Industrial microbiology -- Periodicals; 660.605
• DOI: 10.1016/j.tibtech.2023.01.004
• Languages: English
• ISSNs: 0167-7799

Abstract

Abstract: Recreating 'living organs' with groundbreaking organ-on-a-chip (OOC) technologies is facilitating a new era of drug discovery. Studies by Huh et al. and Ronaldson-Bouchard et al. underscore advances made over a decade, spanning single organ functionality to interconnected organs, that enable examination of drug toxicities and disease pathogenesis in reconstituted tissues.