Design and manufacture of a customized, large-size and high-strength bioactive HA osteoid composite ceramic by stereolithography. Issue 7 (1st April 2023)

• Record Type: Journal Article
• Authors: Liu, Ke; Wu, Xiaopei; Liu, Jiawei; Yang, He; Li, Meng; Qiu, Tong; Dai, Honglian
• Is Part Of: Ceramics international. Volume 49:Issue 7(2023)
• Page Start: 11630
• Page End: 11640
• Publication Date: 2023-04-01
• Subjects: Ceramics -- Periodicals; Céramique industrielle -- Périodiques; Ceramics; Periodicals; Electronic journals; 666
• DOI: 10.1016/j.ceramint.2022.12.010
• Languages: English
• ISSNs: 0272-8842

Abstract

Abstract: Stereolithography (SLA) ceramic printing is still a challenge to establish the adaptability between printing parameters and curing properties, and to meet large-size, high mechanical and good biological properties through structural optimization. In this study, a 3D printed ceramic scaffold with a customized, large-size and high-strength bioactive osteoid structure was achieved by SLA. The interaction effects of laser power, spot spacing, and scanning rate on the curing behaviour of HA slurry were investigated. Next, a compact shell/porous core with different volume ratios was fabricated to meet the requirement of high mechanical strength for load-bearing parts by SLA. Finally, the effect of different microchannel structural units on vascularization was explored based on a modelling algorithm. In conclusion, HA composite scaffolds with large-size, high strength and excellent biological properties were developed by using SLA ceramic printing technology. High strength and structure suitable for blood vessel growth provide a basis for bioceramic repair of large bone defects.