Neuropsychiatric side effects of cyclobenzaprine. (2nd May 2013)

• Record Type: Journal Article
• Authors: Shprecher, David; Sloan, Colgan T; Sederholm, Benson
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-05-02
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2013-008997
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Cyclobenzaprine is commonly used as a muscle relaxant and analgesic. Given its tricyclic properties, serotonin syndrome is a potential side effect of this drug. We report an unusual case of a patient who experienced symptoms of delirium and hyperkinetic movement disorders shortly after initiating treatment with cyclobenzaprine and oxycodone. Symptoms resolved within 48 h of discontinuing cyclobenzaprine. This case serves to remind clinicians to monitor for serotonin syndrome when initiating cyclobenzaprine, and when adding opiate or antidepressant medications to the regimen.