EBV-associated colonic B-cell lymphoma following treatment with infliximab for IBD: a new problem?. (30th September 2013)

• Record Type: Journal Article
• Authors: Allen, Patrick B; Laing, Georgina; Connolly, Aoife; O'Neill, Ciaran
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-09-30
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2013-200423
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Patients with inflammatory bowel disease who do not respond to steroid therapy often require treatment with immunomodulators in an attempt to achieve a response and maintain remission. However, a major concern and controversy is whether these treatments are putting the patients at a significantly increased risk of developing lymphomas. This case reports a patient with severe ulcerative colitis who had been previously treated with azathioprine and infliximab, and subsequently developed diffuse large B-cell colonic lymphoma.