Sarcoid panuveitis associated with etanercept treatment, resolving with adalimumab. (4th September 2013)

• Record Type: Journal Article
• Authors: Dragnev, D; Barr, D; Kulshrestha, M; Shanmugalingam, S
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-09-04
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2013-200552
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : We presented a case of a 54-year-old woman, who developed sarcoidosis uveitis while on treatment with the tumour necrosis factor α (TNFα) antagonist etanercept for rheumatoid arthritis. Her condition improved, but did not recover completely after the medication was stopped. After starting her on another TNFα antagonist, adalimumab, the uveitis recovered completely. Etanercept and adalimumab are from the same class of medication, but have different effects on other mediators and cells, which may explain these discrepancies.