Severe CMV complication following maintenance therapy with rituximab. (9th January 2013)

• Record Type: Journal Article
• Authors: Le Clech, Lenaïg; Ianotto, Jean-Christophe; Quintin-Roue, Isabelle; Tempescul, Adrian
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-01-09
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2012-006672
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Cytomegalovirus (CMV) encephalitis is a rare infection that immunodeficient patients, mainly where HIV-positive, may suffer from. Several cases were described when complications with the treatment with monoclonal antibodies, like rituximab, for malignant lymphomas. We will describe here the case of a patient, who has developed CMV gastritis, then CMV encephalitis after the treatment of a CLL with a chemotherapy and maintenance therapy with rituximab.