Cardiac MRI-confirmed mesalamine-induced myocarditis. (4th September 2015)

• Record Type: Journal Article
• Authors: Baker, William L; Saulsberry, Whitney J; Elliott, Kaitlyn; Parker, Matthew W
• Is Part Of: BMJ case reports. Volume 2015
• Publication Date: 2015-09-04
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2015-210689
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 38-year-old Caucasian man with a medical history significant for inflammatory bowel disease (IBD) and mesalamine use presented to the emergency department with stabbing, pleuritic, substernal chest pain over the previous 2 days. Findings of leucocytosis, elevated cardiac enzymes and inflammatory markers, T-wave or ST-segment abnormalities and left ventricular systolic dysfunction suggested mesalamine-induced myocarditis. However, a cardiac MRI confirmed the diagnosis. Signs and symptoms improved within days of withdrawal of mesalamine, and initiation of corticosteroids and follow-up studies within the next year were unremarkable. Importantly, the diagnosis of mesalamine-induced myocarditis confirmed via cardiac MRI is a step rarely performed in published cases.