Necrotising pneumonia and bronchiectasis in a previously healthy 30-year-old man. (21st January 2015)

• Record Type: Journal Article
• Authors: Blauvelt, David G; Castellanos, Angela; Stern, Theodore A; Puig, Alberto
• Is Part Of: BMJ case reports. Volume 2015
• Publication Date: 2015-01-21
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2014-207747
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : We present a case of a previously healthy 30-year-old man who presented with a necrotising pneumonia and bronchiectasis. His infectious workup revealed a Staphylococcus aureus pneumonia. Since bronchiectasis and necrotising pneumonia are unusual findings in an otherwise healthy person, further investigation was pursued. His workup revealed non-classic cystic fibrosis (CF) and allergic bronchopulmonary aspergillosis (ABPA). This case discusses the differential diagnosis of bronchiectasis, the diagnosis and treatment of ABPA, and the role of CF mutations in the pathogenesis of ABPA.