Guillain-Barré syndrome as a paraneoplastic manifestation of disseminated squamous cell carcinoma. (31st May 2013)

• Record Type: Journal Article
• Authors: Navani, Vishal; Webster, Daniel; Williams, Sion K; Agranoff, Daniel
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-05-31
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2013-009700
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : We describe a 65-year-old woman who developed ascending, symmetrical paraesthesia and weakness. This was on a background of metastatic disseminated squamous cell carcinoma, with a likely recurrent mandibular primary. Serum testing for antiganglioside antibodies was strongly positive. Despite a 5-day course of intravenous immunoglobulin, the patient passed away on day 34 of admission. This is the first case, to our knowledge, of Guillain-Barré syndrome in association with squamous cell carcimoma.