Extranodal lymphoma masquerading as carcinoma of the breast in an HIV-positive male patient. (24th December 2012)

• Record Type: Journal Article
• Authors: Rastogi, Madhup; Revannasiddaiah, Swaroop; Seam, Rajeev Kumar; Gupta, Manoj Kumar; Gupta, Manish
• Is Part Of: BMJ case reports. Volume 2012
• Publication Date: 2012-12-24
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2012-007472
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : This report describes a male patient infected with the HIV, with antiretroviral therapy (ART)-induced gynaecomastia. He presented with a right-sided breast mass which clinically resembled a carcinoma. A core biopsy suggested non-Hodgkin's lymphoma of diffuse large B cell histology. Also presented are his 18-fluoro-deoxy-glucose - positron emission tomography (FDG PET)-CT scan findings which showed a highly avid mass (standardised uptake value ( SUV) 34.5 ) in his right breast. In spite of a very good clinical response after the first cycle of chemotherapy, his disease relapsed at multiple sites and progressed early. This case illustrates the aggressive course of HIV-associated extranodal lymphomas, and also highlights the issues concerning the use of ART and chemotherapy.