A complex neurological presentation of syphilis. (2nd August 2013)

• Record Type: Journal Article
• Authors: Kamath, Max; Rizvi, Maleeha; O'Nions, Jenny; Brook, Gary
• Is Part Of: BMJ case reports. Volume 2013
• Publication Date: 2013-08-02
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr-2013-200309
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : Syphilis is a contagious sexually transmitted infection notable for its complex array of systemic presentations. It is caused by the spirochaete Treponema pallidum and although once considered to be a largely historical condition in the UK, the recent rise in incidence makes syphilis increasingly relevant when considering unusual presentations in at-risk patients. The disease has three stages: primary, secondary and tertiary. The tertiary stage is associated with a plethora of neurological features ranging from psychosis to seizure caused by direct invasion of the spirochaete into the central nervous system. Here we describe the case of a 45-year-old man presenting with tonic clonic seizures on a background of balance and visual problems. Following normal examination and routine investigations further serology confirmed a diagnosis of neurosyphilis. The patient was started on appropriate treatment and made an excellent clinical recovery.