Breast Reconstruction With Autologous Fat Graft Mixed With Platelet-Rich Plasma. (August 2013)

• Record Type: Journal Article
• Authors: Gentile, Pietro; Di Pasquali, Camilla; Bocchini, Ilaria; Floris, Micol; Eleonora, Tati; Fiaschetti, Valeria; Floris, Roberto; Cervelli, Valerio
• Is Part Of: Surgical innovation. Volume 20:Number 4(2013)
• Page Start: 370
• Page End: 376
• Publication Date: 2013-08
• Subjects: platelet-rich plasma -- fat graft with platelet-rich plasma -- breast fat graft -- PRP; Surgery, Operative -- Periodicals; Endoscopic surgery -- Periodicals; Laparoscopic surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgical Procedures, Minimally Invasive -- Periodicals; Diffusion of Innovation -- Periodicals; Chirurgie opératoire -- Périodiques; Chirurgie endoscopique -- Périodiques; Chirurgie laparoscopique -- Périodiques; 617.91
• DOI: 10.1177/1553350612458544
• Languages: English
• ISSNs: 1553-3506

Abstract

Background . The purpose of this study was to review the authors' experience of fat grafting, evaluating the effects related to the use of fat grafting with platelet-rich plasma (PRP) in the improvement of fat volume in breast reconstruction and comparing the results with a control group (only centrifuged fat grafting). Methods . A total of 50 patients aged between 19 and 60 years affected by breast soft-tissue defects were analyzed at the Plastic and Reconstructive Department of the University of Tor Vergata. They were treated with fat grafting + PRP. The control group (50 patients with breast soft-tissue defects) were treated with centrifuged fat grafting injection according to Coleman's procedure. Results . The patients treated with PRP added to the autologous fat grafts showed a 69% maintenance of the contour restoring and of 3-dimensional volume after 1 year, whereas the patients of the control group treated with centrifuged fat grafting showed a 39% maintenance. Conclusion . PRP mixed with fat grafting leads to an improvement in maintaining breast volume in patients affected by breast soft-tissue defects.