Paraquat-induced convulsion and death: a report of five cases. (September 2013)

• Record Type: Journal Article
• Authors: Huang, Changbao; Zhang, Xigang; Jiang, Yun; Li, Guang; Wang, Haochun; Tang, Xueping; Wang, Qunli
• Is Part Of: Toxicology and industrial health. Volume 29:Number 8(2013)
• Page Start: 722
• Page End: 727
• Publication Date: 2013-09
• Subjects: Paraquat -- convulsive -- seizure -- poisoning -- complications; Toxicology, Experimental -- Periodicals; Industrial toxicology -- Periodicals; 615.9
• DOI: 10.1177/0748233712442712
• Languages: English
• ISSNs: 0748-2337

Abstract

Paraquat (PQ) is a potent toxicant for humans, and poisoning with PQ is associated with high mortality. Patients with severe PQ-induced poisoning may die of multiple organ failure involving the circulatory and respiratory systems. Death resulting from epilepsy-like convulsions, which are infrequently noted reported with PQ poisoning, is observed clinically with this condition. This study presents the clinical data of five patients with severe PQ-induced poisoning who died of epilepsy-like convulsions, and related publications were reviewed in order to investigate the pathogenesis, clinical manifestations, and prognosis of these convulsions. Our results may help prevent this event and improve the success of treatment.