The Increasing Prevalence of Clindamycin Resistance in Staphylococcus aureus Isolates in Children with Head and Neck Abscesses. Issue 2 (2011)

• Record Type: Journal Article
• Authors: Alexander, Ashlin J.; Richardson, Susan E.; Sharma, Alok; Campisi, Paolo
• Is Part Of: Canadian journal of infectious diseases & medical microbiology =. Volume 22:Issue 2(2011)
• Page Start: 49
• Page End: 51
• Publication Date: 2011
• Subjects: Abscess -- Clindamycin resistance -- Head and neck; Communicable diseases -- Periodicals; Infection -- Periodicals; Communicable diseases; Infection; Communicable Diseases; Communicable Disease Control; Electronic journals; Periodicals; Fulltext; Internet Resources; Periodicals; 616.9
• DOI: 10.1155/2011/261519
• Languages: English
• ISSNs: 1712-9532

Abstract

Abstract : OBJECTIVE: To retrospectively review trends in clindamycin resistance among Staphylococcus aureus head and neck abscesses between January 2000 and June 2008. METHODS: Between January 2000 and June 2008, inpatient and out-patient S aureus isolates were reviewed for antibiotic susceptibility. In particular, cultures from 153 abscesses in the head and neck region were assessed for clindamycin and methicillin resistance patterns. RESULTS: Annual clindamycin resistance rates for all S aureus isolates, and specifically for S aureus head and neck abscesses, revealed concerning levels of clindamycin and methicillin resistance. After 2002, the mean clindamycin resistance rate in head and neck abscesses was approximately 27%. The number of new cases of methicillin-resistant S aureus per year increased from four cases in 2000 to 44 cases in 2007. CONCLUSION: Antibiotic resistance should be considered following failed empirical therapy of head and neck abscesses with clindamycin.