Ceftobiprole: First Reported Experience in Osteomyelitis. Issue 3 (2010)

• Record Type: Journal Article
• Authors: MacDonald, A; Dow, G
• Is Part Of: Canadian journal of infectious diseases & medical microbiology =. Volume 21:Issue 3(2010)
• Page Start: 138
• Page End: 140
• Publication Date: 2010
• Subjects: Ceftobiprole -- Diabetic foot -- Osteomyelitis; Communicable diseases -- Periodicals; Infection -- Periodicals; Communicable diseases; Infection; Communicable Diseases; Communicable Disease Control; Electronic journals; Periodicals; Fulltext; Internet Resources; Periodicals; 616.9
• DOI: 10.1155/2010/296760
• Languages: English
• ISSNs: 1712-9532

Abstract

Abstract : A 74-year-old man with long-standing diabetes presented with advanced infection of the right forefoot associated with septic arthritis and osteomyelitis involving the second and third metatarsophalangeal joints. Polymicrobial infection, which included methicillin-resistant Staphylococcus aureus, was documented. First-line antibiotic therapy, which included vancomycin, was not tolerated. A durable cure was obtained following a six-week course of intravenous ceftobiprole medocaril combined with local surgery. The present report is the first to administer intravenous ceftobiprole medocaril to a patient with methicillin-resistant S aureus -associated septic arthritis and osteomyelitis.