Genetic Detection of Quinolone Resistance in Haemophilus parainfluenzae: Mutations in the Quinolone Resistance-Determining Regions of gyrA and parC. Issue 1 (2010)

• Record Type: Journal Article
• Authors: Law, Dennis KS; Shuel, Michelle; Bekal, Sadjia; Bryce, Elizabeth; Tsang, Raymond SW
• Is Part Of: Canadian journal of infectious diseases & medical microbiology =. Volume 21:Issue 1(2010)
• Page Start: e20
• Page End: e22
• Publication Date: 2010
• Subjects: Genetic detection -- Haemophilus parainfluenzae -- Quinolone resistance; Communicable diseases -- Periodicals; Infection -- Periodicals; Communicable diseases; Infection; Communicable Diseases; Communicable Disease Control; Electronic journals; Periodicals; Fulltext; Internet Resources; Periodicals; 616.9
• DOI: 10.1155/2010/525919
• Languages: English
• ISSNs: 1712-9532

Abstract

Abstract : The quinolone resistance-determining regions of gyr A and par C of both quinolone-sensitive and quinolone-resistant Haemophilus parainfluenzae strains were amplified and sequenced. Similar to Haemophilus influenzae, resistance to quinolones in H parainfluenzae is associated with mutations in the quinolone resistance-determining regions of both gyr A and par C. The present study discusses the importance of this finding.