Establishing Sickle Cell Disease Stroke Prevention Teams in Africa is Feasible: Program Evaluation Using the RE-AIM Framework. Issue 1 (18th May 2021)

• Record Type: Journal Article
• Authors: Ghafuri, Djamila L.; Abdullahi, Shehu U.; Dambatta, Abdu H.; Galadanci, Jamil; Tabari, Musa A.; Bello-Manga, Halima; Idris, Nura; Inuwa, Hauwa; Tijjani, Aliyu; Suleiman, Aisha A.; Jibir, Binta W.; Gambo, Safiya; Gambo, Awwal I.; Khalifa, Yusuf; Haliru, Lawal; Abdulrasheed, Sani; Zakari, Mohammed A.; Greene, Brittany C.; Trevathan, Edwin; Jordan, Lori C.; Aliyu, Muktar H.; Baumann, Ana A.; DeBaun, Michael R.
• Is Part Of: Journal of pediatric hematology/oncology. Volume 44:Issue 1(2022)
• Page Start: e56
• Page End: e61
• Publication Date: 2021-05-18
• Subjects: sickle cell -- stroke prevention -- low-resource setting -- Nigeria -- RE-AIM; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000002179
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate a Stroke Prevention Team's readiness to prevent strokes in children with sickle cell anemia living in northern Nigeria. The NIH sponsored Stroke Prevention Trial in Nigeria included a goal of a sustainable stroke prevention program. The program's 1-year reach for transcranial Doppler screening was 14.7% (4710/32, 000) of which 6.0% (281/4710) had abnormal velocities (≥200 cm/s). All participants with abnormal transcranial Doppler velocities were started on hydroxyurea ( effectiveness ). The leaders of all 5 hospitals agreed to adopt the program. After 1 year, program- implementation and maintenance rates were 100%, demonstrating the program's feasibility and short-term sustainability.