Outcomes of Liu's aortic root repair and valve preservation in patients with type A dissection and aortic regurgitation. (26th January 2021)

• Record Type: Journal Article
• Authors: Piao, Hulin; Wang, Yong; Huang, Maoxun; Zhu, Zhicheng; Xu, Rihao; Wang, Tiance; Li, Dan; Liu, Kexiang
• Is Part Of: Interactive cardiovascular and thoracic surgery. Volume 32:Number 5(2021)
• Page Start: 781
• Page End: 788
• Publication Date: 2021-01-26
• Subjects: Aortic dissection -- Moderate-to-severe aortic regurgitation -- Aortic root repair -- Valve preservation; Chest -- Surgery -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.1
• DOI: 10.1093/icvts/ivaa322
• Languages: English
• ISSNs: 1569-9293

Abstract

Abstract: : OBJECTIVES: To evaluate short- and medium-term outcomes following Liu's aortic root repair and valve preservation in patients with acute type A aortic dissection complicated by moderate-to-severe aortic regurgitation (AR). METHODS: From October 2011 to July 2018, a total of 324 consecutive patients underwent emergency surgery for acute type A aortic dissection. There were 122 patients (38%) with moderate-to-severe AR, of whom 82 (67%) underwent Liu's aortic root repair and valve preservation. Aortic computed tomography angiography and echocardiography were performed at discharge, 6 and 12 months postoperatively, and annually thereafter. We focused on assessing the survival and aortic root and valve durability in the 82 patients. RESULTS: The 30-day, 1-year, 3-year and 6-year survival estimates were 94%, 90%, 85% and 81%, respectively. At a median follow-up of 36.5 (interquartile range 24.9–50.9) months, all patients were free from reoperation. No residual false lumens in the aortic root, recurrent aortic root dissections or aortic root pseudoaneurysms were observed during the follow-up period. Only 1 patient (1%) presented with moderate AR at 6 months, which remained asymptomatic with no significant changes over a 3-year period. The remaining patients showed satisfactory valve function with an AR grade of mild (27%) or trace or none (72%). In the competing risk analysis, the incidence of recurrence of AR was 2% at 8 years. CONCLUSIONS: Liu's aortic root repair and valve preservation is a safe and effective operative strategy that achieves favourable short- and medium-term outcomes for acute type A aortic dissection with moderate-to-severe AR.