Solid pancreatic pseudopapillary tumor managed laparoscopically: A case report and review of the literature. (2018)

• Record Type: Journal Article
• Authors: Cuccurullo, D.; Carbone, G.; Iovino, M.G.; De Rosa, I.; Fabozzi, M.; Corcione, F.
• Is Part Of: International journal of surgery case reports. Volume 45(2018)
• Page Start: 4
• Page End: 8
• Publication Date: 2018
• Subjects: Pancreatic pseudopapillary neoplasm -- Pancreatic tumor -- Laparoscopic surgery; Surgery -- Periodicals; Surgical Procedures, Operative -- Periodicals; Surgery; Electronic journals; Periodicals; 617.005
• DOI: 10.1016/j.ijscr.2017.12.043
• Languages: English
• ISSNs: 2210-2612

Abstract

Highlights: Solid pancreatic pseudopapillary tumors are a rare neoplasms with not well known pathogenesis. Imaging is not able to provide a precise diagnostic orientation. The essential role is played by surgery and histological examination. Immunohistochemistry shows a possible correlation between the Beta-catenin mutations or alteration of the E-cadherin and tumor development. Laparoscopic technique has proven to be the gold standard for the countless advantages found compared to the open technique. Abstract: Background: Solid pancreatic pseudopapillary tumors are a rare neoplasms, about 1–3% of all pancreatic neoplasms. This cancer mainly affects women between the third and fourth decade of life. They are not well known; the molecular origins represent a low degree of malignancy, in which the complete resection is curative. We report our experience with a case report of SPT in a young man. Presentation of case: Thirty-six years old male patient with a mass about 10 cm in the pancreatic tail and splenic ilum. After following CT and MR, the patient was subjected to surgery. Histophatological result was solid tumor pseudopapillary of pancreas with no pathological lymph nodes. Discussion and conclusion: Solid pseudopapillary neoplasm shows histological characteristic solid and pseudopapillary proliferation. Immunohistochemistry detects, among the causes of tumor development, a correlation between the Beta-catenin mutations, alteration of the E-cadherin. In the most cases, therapy is surgical treatment with laparoscopic.