Zn Nanoparticles Modified Screen Printed Carbon Electrode as a Promising Sensor for Insulin Determination. Issue 3 (30th October 2020)

• Record Type: Journal Article
• Authors: Šišoláková, Ivana; Hovancová, Jana; Chovancová, Frederika; Oriňaková, Renáta; Maskaľová, Iveta; Oriňak, Andrej; Radoňak, Jozef
• Is Part Of: Electroanalysis. Volume 33:Issue 3(2021)
• Page Start: 627
• Page End: 634
• Publication Date: 2020-10-30
• Subjects: insulin -- diabetes mellitus -- zinc nanoparticles -- carbon electrodes -- electrochemical sensor; Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.202060417
• Languages: English
• ISSNs: 1040-0397

Abstract

Abstract: Screen printed carbon electrodes (SPCEs) modified by a combination of chitosan, multi walled carbon nanotubes (MWCNTs) and zinc nanoparticles (ZnNPs) were studied for the first time as a suitable candidate for non‐enzymatic insulin determination. In an effort to find the most suitable modification for electrochemical insulin determination, the stability, analytical characteristics, and selectivity were determined. The results confirmed that the ZnNPs/chitosan‐MWCNTs prepared with the Zn deposition time of 45 s displayed the best electrocatalytic activity towards insulin oxidation in a wide linear concentration range (0.5 μM to 5 μM), with low limit of detection and high sensitivity. Abstract :