Corrosion fatigue behavior of additively manufactured biodegradable porous zinc. (1st April 2020)

• Record Type: Journal Article
• Authors: Li, Y.; Li, W.; Bobbert, F.S.L.; Lietaert, K.; Dong, J-H.; Leeflang, M.A.; Zhou, J.; Zadpoor, A.A.
• Is Part Of: Acta biomaterialia. Volume 106(2020)
• Page Start: 439
• Page End: 449
• Publication Date: 2020-04-01
• Subjects: Additive manufacturing -- Biodegradation -- Corrosion fatigue -- Functionally graded structure -- Zinc; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1016/j.actbio.2020.02.001
• Languages: English
• ISSNs: 1742-7061

Abstract

Abstract: Additively manufactured (AM) biodegradable porous zinc exhibits great potential as a promising bone-substituting biomaterial. However, there is no information whatsoever available regarding its corrosion fatigue behavior. In this study, we used direct metal printing to fabricate topologically ordered biodegradable porous zinc based on a diamond unit cell. We compared the compression-compression fatigue behavior of AM porous zinc in air and in revised simulated body fluid (r-SBF). The fatigue strength of AM porous zinc was high in air ( i.e., 70% of its yield strength) and even higher in r-SBF ( i.e., 80% of its yield strength). The high value of the relative fatigue strength in air could be attributed to the good ductility of pure zinc itself. The formation of corrosion products around the strut junctions might explain the higher fatigue strength of AM zinc in r-SBF. Furthermore, we compared the fatigue behavior of a uniform design of the AM porous zinc with a functionally graded design. The functionally graded structure exhibited higher relative fatigue strengths than the uniform structure. The inspection of the fatigue crack distribution revealed that the functionally graded design controlled the sequence of crack initiation, which occurred early in the thicker struts and moved towards the thinner struts over time. The theoretical fatigue life models suggest that optimizing the functionally graded structure could be used as an effective means to improve the fatigue life of AM porous zinc. In conclusion, the favorable fatigue behavior of AM porous zinc further highlights its potential as a promising bone-substituting biomaterial. Statement of Significance: Additively manufactured (AM) biodegradable porous zinc exhibits great potential for the treatment of large bony defects. However, there is no information available regarding its corrosion fatigue behavior. Here, we compared the fatigue behavior of AM porous zinc in air and in revised simulated body fluid (r-SBF). The fatigue strength of AM porous Zn was even higher in r-SBF than in air, which were attributed to the formation of corrosion products. Furthermore, we found that the functionally graded structure controlled the sequence of crack initiation in differently sized struts and exhibited higher relative fatigue strengths than the uniform structure, suggesting that optimizing the functionally graded structure could be an effective means to improve the fatigue life of AM porous Zn. Graphical abstract: Image, graphical abstract