Sperm selection strategies and their impact on assisted reproductive technology outcomes. (28th June 2020)

• Record Type: Journal Article
• Authors: Pinto, Soraia; Carrageta, David F.; Alves, Marco G.; Rocha, António; Agarwal, Ashok; Barros, Alberto; Oliveira, Pedro F.
• Other Names: Agarwal Ashok guestEditor.; Baskaran Saradha guestEditor.; Durairajanayagam Damayanthi guestEditor.; Vij Sarah guestEditor.
• Is Part Of: Andrologia. Volume 53:Number 2(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-06-28
• Subjects: ART -- ICSI -- IUI -- IVF -- spermatozoa; Andrology -- Periodicals; Infertility, Male -- Periodicals; 616.69
• DOI: 10.1111/and.13725
• Languages: English
• ISSNs: 0303-4569

Abstract

Abstract: The application of assisted reproductive technologies (ART) has revolutionised the treatment of human infertility, giving hope to the patients previously considered incapable of establishing pregnancy. While semen analysis is performed to access whether a sample has an adequate number of viable, motile and morphologically normal sperm cells able to achieve fertilisation, sperm selection techniques for ART aim to isolate the most competent spermatozoon which is characterised by the highest fertilising potential. Based on the semen analysis results, the correct sperm selection technique must be chosen and applied. In this review, different sperm selection strategies for retrieving spermatozoa with the highest fertilising potential and their impact on ART outcomes are discussed. In addition, advantages and disadvantages of each method and the best suited techniques for each clinical scenario are described.