FDG-Avid Tracheal Mass and Cartilage Involvements in ANCA-Negative Granulomatosis With Polyangiitis. (January 2022)

• Record Type: Journal Article
• Authors: Tanaka, Hiroki; Hosono, Makoto; Kawabata, Kazuna; Kageyama, Goichi; Yamashita, Mai
• Is Part Of: Clinical nuclear medicine. Volume 47:Number 1(2022)
• Publication Date: 2022-01
• Subjects: ANCA-negative -- granulomatosis with polyangiitis -- FDG; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003848
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 57-year-old woman was referred for progressive dyspnea. CT showed a tracheal mass, suspicious of tracheal neoplasm. The lesion was partially resected, and nonspecific granulation tissue was observed on histology. Her symptoms and CT findings worsened. FDG PET/CT showed increased FDG accumulation in the nasal septum and left eustachian tube in addition to the tracheobronchial lesions. Although the patient was ANCA (antineutrophil cytoplasmic antibodies) negative, a differential diagnosis of granulomatosis with polyangiitis was established and confirmed pathologically. FDG PET/CT was useful for diagnosis of ANCA-negative granulomatosis with polyangiitis, in which tracheobronchial and cartilage lesions were prominent.