Stress Disorders and the Risk of Nonfatal Suicide Attempts in the Danish Population. Issue 6 (28th May 2021)

• Record Type: Journal Article
• Authors: Street, Amy E.; Jiang, Tammy; Horváth‐Puhó, Erzsébet; Rosellini, Anthony J.; Lash, Timothy L.; Sørensen, Henrik T.; Gradus, Jaimie L.
• Other Names: Kerig Patricia K. guestEditor.
• Is Part Of: Journal of traumatic stress. Volume 34:Issue 6(2021)
• Page Start: 1108
• Page End: 1117
• Publication Date: 2021-05-28
• Subjects: Post-traumatic stress disorder -- Periodicals; 616.8521
• DOI: 10.1002/jts.22695
• Languages: English
• ISSNs: 0894-9867

Abstract

Abstract: Accurate documentation of the associations between stress disorders and suicide attempts provides important information about a high‐risk population and target group for preventative interventions. In this case‐cohort study, cases were all individuals born or residing in Denmark who made a nonfatal suicide attempt during 1995–2015 ( n = 22, 974). The comparison subcohort included a 5% random sample of the Danish population on January 1, 1995 ( n = 265, 183). Stress disorder diagnoses and suicide attempts were identified using ICD‐10 codes from national medical registries. The presence of any stress disorder substantially increased the rate of suicide attempts versus the comparison subcohort, rate per 100, 000 person‐years (PYs) = 604 vs. 13. We observed associations between each type of stress disorder and suicide attempts, hazard ratios ( HR s) = 10.1–37.6, even after adjustment for potential confounders, adjusted HR s = 1.8–8.3, with the strongest associations for adjustment disorder relative to other diagnoses. After adjusting for demographic and health variables, the rate of suicide attempts among individuals with any stress disorder diagnosis was nearly 13 times the suicide attempt rate in the comparison cohort. A bias analysis demonstrated that associations remained robust despite potential differential misclassification of suicide attempts. Study strengths included the use of individual‐level data linked across administrative and medical registries in the setting of universal health care and the use of longitudinal analyses capturing data over 20 years. The study demonstrated associations between the full range of stress disorders and suicide attempts, extending research specific to posttraumatic stress disorder. 抽象: Traditional and Simplified Chinese Abstracts by the Asian Society for Traumatic Stress Studies (AsianSTSS) 簡體及繁體中文撮要由亞洲創傷心理研究學會翻譯 Traditional Chinese 丹麥人口中的壓力症及非致命性自殺企圖的風險 摘要 準確記錄壓力症及自殺企圖之間的聯繫, 為預防干預提供了關於高危人群及目標群體的重要信息。在本病例隊列研究中, 病例均為1995‐2015年期間在丹麥出生或居住的非致命性自殺企圖的人(n = 22, 974)。比較亞隊列包括1995年1月1日丹麥人口的5%隨機樣本(n = 265, 183)。使用國家醫療登記處的ICD‐10編碼確定壓力症診斷及自殺企圖。與比較亞群相比, 任何壓力症的存在顯著增加了自殺企圖的比率, 每10萬人年的比率(PYs) = 604 vs. 13。我們觀察到每種類型的壓力症及自殺企圖之間的聯繫, 危險比(HRs) = 10.1‐37.6, 即使在調整了潛在的混雜因素後, 調整的HRs = 1.8‐8.3, 與適應障礙的最強關聯相對於其他診斷。在對人口統計學及健康變量進行調整後, 有任何壓力症診斷的人的自殺企圖率是對比隊列中自殺企圖率的近13倍。一項偏差分析表明, 儘管自殺企圖存在潛在的差異錯誤分類, 但相關性仍然強大。研究的優勢包括:在全民保健的背景下, 使用與行政及醫療登記處聯繫在一起的個人層面的數據, 以及使用收集20多年數據的縱向分析。這項研究證明了各種壓力症及自殺企圖之間的聯繫, 將研究擴展到創傷後壓力症。 Simplified Chinese 丹麦人口中的压力症及非致命性自杀企图的风险 摘要 准确记录压力症及自杀企图之间的联系, 为预防干预提供了关于高危人群及目标群体的重要信息。在本病例队列研究中, 病例均为1995‐2015年期间在丹麦出生或居住的非致命性自杀企图的人(n = 22, 974)。比较亚队列包括1995年1月1日丹麦人口的5%随机样本(n = 265, 183)。使用国家医疗登记处的ICD‐10编码确定压力症诊断及自杀企图。与比较亚群相比, 任何压力症的存在显著增加了自杀企图的比率, 每10万人年的比率(PYs) = 604 vs. 13。我们观察到每种类型的压力症及自杀企图之间的联系, 危险比(HRs) = 10.1‐37.6, 即使在调整了潜在的混杂因素后, 调整的HRs = 1.8‐8.3, 与适应障碍的最强关联相对于其他诊断。在对人口统计学及健康变量进行调整后, 有任何压力症诊断的人的自杀企图率是对比队列中自杀企图率的近13倍。一项偏差分析表明, 尽管自杀企图存在潜在的差异错误分类, 但相关性仍然强大。研究的优势包括:在全民保健的背景下, 使用与行政及医疗登记处联系在一起的个人层面的数据, 以及使用收集20多年数据的纵向分析。这项研究证明了各种压力症及自杀企图之间的联系, 将研究扩展到创伤后压力症。