GW24-e3549 Role of heart-type fatty acid-binding protein in assessing prognosis of acute pulmonary embolism. (1st October 2013)

• Record Type: Journal Article
• Authors: Li, ; Li, Bingong
• Is Part Of: Heart. Volume 99(2013)Supplement 3
• Page Start: A255
• Page End: A255
• Publication Date: 2013-10-01
• Subjects: Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/heartjnl-2013-304613.718
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Objectives: To study the role of heart-type fatty acid-binding protein (H-FABP) in assessing prognosis of acute pulmonary embolism (APE). Methods: The levels of plasmid H-FABP and cTnI and D-Dimer in 72 patients with APE and 30 healthy controls were determined. The associations between the biomarkers and the severe complications were determined though a logistic regression model. Results: The levels of D-Dimer in patients with APE were significantly higher than that in healthy controls (P < 0.01). The incidence of severe complications in the H-FABP-positive group of APE was higher than in the H-FABP negative group (66.7% vs 3.5%, P < 0.05). By logistic regression, elevated H-FABP was associated with a 50.44-fold increase in the death or complication risk (95%CI: 7.40-342.88, P < 0.001). Conclusions: The H-FABP might be a useful biomarker for prediction prognosis of patients with APE.