Initial experience with the new type A arch dissection stent: restoration of supra-aortic vessel perfusion. (19th May 2021)
- Record Type:
- Journal Article
- Title:
- Initial experience with the new type A arch dissection stent: restoration of supra-aortic vessel perfusion. (19th May 2021)
- Main Title:
- Initial experience with the new type A arch dissection stent: restoration of supra-aortic vessel perfusion
- Authors:
- Montagner, Matteo
Kofler, Markus
Heck, Roland
Buz, Semih
Starck, Christoph
Kurz, Stephan
Falk, Volkmar
Kempfert, Jörg - Abstract:
- Abstract: OBJECTIVES: The goal of the present study is to investigate changes in supra-aortic vessel perfusion after implantation of the non-covered Ascyrus Medical Dissection Stent (AMDS) for surgical treatment of acute type A aortic dissection. METHODS: From 2017 to 2020, 16 consecutive patients treated with AMDS and involvement (dissection to total occlusion) of at least 1 supra-aortic vessel were included in the study. Centre-line based computed tomography measurements of true, false and total lumen area using Terarecon software were performed before and after surgery. Changes in the true lumen area were indexed to the entire vessel area. The paired sample t -test was used to assess the significance of the observed differences. RESULTS: Analysis of supra-aortic vessels and the descending aorta showed significant improvement in true lumen perfusion after the AMDS was implanted. The indexed true lumen area increased postoperatively by 72%, 112% and 30% in the innominate, right and left common carotid arteries, respectively. Total occlusions of both common carotid arteries recovered completely after surgical treatment. The proximal- and the mid-descending aorta showed a 78% and 48% improvement of the indexed true lumen area, respectively. CONCLUSIONS: Arch repair using AMDS shows promising results in the treatment of acute type A aortic dissection. Quantitative measurements of true and false lumen perfusion demonstrated a significant increase in true lumen area and a 100%Abstract: OBJECTIVES: The goal of the present study is to investigate changes in supra-aortic vessel perfusion after implantation of the non-covered Ascyrus Medical Dissection Stent (AMDS) for surgical treatment of acute type A aortic dissection. METHODS: From 2017 to 2020, 16 consecutive patients treated with AMDS and involvement (dissection to total occlusion) of at least 1 supra-aortic vessel were included in the study. Centre-line based computed tomography measurements of true, false and total lumen area using Terarecon software were performed before and after surgery. Changes in the true lumen area were indexed to the entire vessel area. The paired sample t -test was used to assess the significance of the observed differences. RESULTS: Analysis of supra-aortic vessels and the descending aorta showed significant improvement in true lumen perfusion after the AMDS was implanted. The indexed true lumen area increased postoperatively by 72%, 112% and 30% in the innominate, right and left common carotid arteries, respectively. Total occlusions of both common carotid arteries recovered completely after surgical treatment. The proximal- and the mid-descending aorta showed a 78% and 48% improvement of the indexed true lumen area, respectively. CONCLUSIONS: Arch repair using AMDS shows promising results in the treatment of acute type A aortic dissection. Quantitative measurements of true and false lumen perfusion demonstrated a significant increase in true lumen area and a 100% regression of totally occluded supra-aortic branches. Further examination in a larger cohort of patients and comparison with isolated hemiarch repair are needed to confirm positive vascular remodelling after an AMDS implant. … (more)
- Is Part Of:
- Interactive cardiovascular and thoracic surgery. Volume 33:Number 2(2021)
- Journal:
- Interactive cardiovascular and thoracic surgery
- Issue:
- Volume 33:Number 2(2021)
- Issue Display:
- Volume 33, Issue 2 (2021)
- Year:
- 2021
- Volume:
- 33
- Issue:
- 2
- Issue Sort Value:
- 2021-0033-0002-0000
- Page Start:
- 276
- Page End:
- 283
- Publication Date:
- 2021-05-19
- Subjects:
- Type A aortic dissection -- Arch repair -- Cerebral malperfusion -- DeBakey I -- Ascyrus Medical Dissection Stent
Chest -- Surgery -- Periodicals
Cardiovascular system -- Diseases -- Periodicals
616.1 - Journal URLs:
- http://icvts.oxfordjournals.org/ ↗
http://ukcatalogue.oup.com/ ↗ - DOI:
- 10.1093/icvts/ivab085 ↗
- Languages:
- English
- ISSNs:
- 1569-9293
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4531.871920
British Library DSC - BLDSS-3PM
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- 25824.xml