Synthesis, Spectral Characterization, and Biological Activities of Some Metal Complexes Bearing an Unsymmetrical Salen-Type Ligand, (Z)-1-(((2-((E)-(2-Hydroxy-6-methoxybenzylidene)amino)phenyl)amino) methylene) Naphthalen-2(1H)-one. (4th February 2023)

• Record Type: Journal Article
• Authors: Nguyen, Quang Trung; Pham Thi, Phuong Nam; Bui, Quang Do; Nguyen, Van Tuyen
• Other Names: Suneja Arun Academic Editor.
• Is Part Of: Heteroatom chemistry. Volume 2023(2023)
• Publication Date: 2023-02-04
• Subjects: Heterocyclic chemistry -- Periodicals; 547.59
• DOI: 10.1155/2023/4563958
• Languages: English
• ISSNs: 1042-7163

Abstract

Abstract : An unsymmetrical salen-type Schiff base ligand, (Z)-1-(((2-((E)-(2-hydroxy-6-methoxybenzylidene)amino)phenyl)amino)methylene)naphthalen-2(1H)-one, and its Zn(II), Cu(II), Co(II), Mn(II), and Fe(III) complexes were synthesized and characterized by mass (MS), nuclear magnetic resonance (NMR), infrared (IR), ultraviolet-visible (UV-Vis) spectra, and effective magnetic moments. The thermal analyses of the obtained ligand and metal complexes were conducted by thermogravimetric analysis (TGA). Antimicrobial activity of the unsymmetrical Schiff base ligand and its metal complexes were examined for Staphylococcus aureus as Gram-positive bacteria and Escherichia coli as Gram-negative bacteria. In vitro anticancer property of synthetic compounds was estimated against human cancer cell lines, a subline of Hela tumor cell line (KB), and a human liver cancer cell line (HepG-2) as well.