Paroxysmal Cold Hemoglobinuria: Diagnosis From the Blood Smear. Issue 2 (25th March 2022)

• Record Type: Journal Article
• Authors: Radhakrishnan, Kottayam; Downie, Peter A.; Earley, Ciara M.
• Is Part Of: Journal of pediatric hematology/oncology. Volume 44:Issue 2(2022)
• Page Start: 60
• Page End: 61
• Publication Date: 2022-03-25
• Subjects: paroxysmal cold hemoglobinuria -- erythrophagocytosis -- neutrophils -- Donath-Landsteiner; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; 618.9215
• DOI: 10.1097/MPH.0000000000002401
• Languages: English
• ISSNs: 1077-4114

Abstract

Abstract : Phagocytosis of red cells by neutrophils, referred to as neutrophil erythrophagocytosis, on the blood smear as a helpful diagnostic sign of paroxysmal cold hemoglobinuria is underrecognized. We present a child with paroxysmal cold hemoglobinuria and prominent neutrophil erythrophagocytosis to highlight the importance of this finding in the diagnosis of paroxysmal cold hemoglobinuria.