Neuroendocrine Tumors of the Submandibular Gland: Literature Review and Report of a Case. (February 2013)

• Record Type: Journal Article
• Authors: Petrone, Gianluigi; Santoro, Angela; Angrisani, Basilio; Novello, Mariangela; Scarano, Emanuele; Rindi, Guido; Lauriola, Libero
• Is Part Of: International journal of surgical pathology. Volume 21:Number 1(2013)
• Page Start: 85
• Page End: 88
• Publication Date: 2013-02
• Subjects: neuroendocrine tumors -- salivary gland -- immunohistochemistry; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/1066896912446747
• Languages: English
• ISSNs: 1066-8969

Abstract

Primary salivary neuroendocrine neoplasms are extremely rare, with only 1 case of carcinoid tumor and 7 cases of primary large-cell neuroendocrine carcinomas having been reported. Salivary small-cell neuroendocrine carcinomas are more frequent, accounting for less than 2% of all salivary malignancies. In addition to a literature review on the subject, the authors describe a rare case of malignant intermediate-grade neuroendocrine tumor of the submandibular gland.