Resistance (Weight Lifting) Training in an Adolescent With McArdle Disease. (June 2013)

• Record Type: Journal Article
• Authors: García-Benítez, Sergio; Fleck, Steven J.; Naclerio, Fernando; Martín, Miguel Angel; Lucia, Alejandro
• Is Part Of: Journal of child neurology. Volume 28:Number 6(2013)
• Page Start: 805
• Page End: 808
• Publication Date: 2013-06
• Subjects: glycogenosis -- exercise -- muscle damage -- CK -- McArdle disease; Nervous system -- Diseases -- Periodicals; 618.928
• DOI: 10.1177/0883073812451328
• Languages: English
• ISSNs: 0883-0738

Abstract

Owing to the risk of severe rhabdomyolysis, clinicians advise McArdle disease patients to refrain from strenuous exercise, particularly weight lifting. A 15-year-old male McArdle disease patient performed a 6-week, supervised, light- to moderate-intensity (∼65-70% of one-repetition-maximum) resistance (weight lifting) training program (2 sessions/week). Training resulted in ∼27% and ∼6% increase in one-repetition-maximum bench press and multipower squat performance while inducing no myoglobinuria. The patient changed to a lower disease severity class, that is, he became virtually asymptomatic in terms of exercise limitations. The authors' preliminary data suggest that supervised, light to moderate resistance training is feasible in children with McArdle disease and has potential clinical benefits.