A case report: extensive myocardial calcification and non-ischaemic cardiomyopathy related to past sepsis. Issue 2 (18th February 2021)

• Record Type: Journal Article
• Authors: Lim, Anthony; Be, Kim Kuy; Wong, Chiew
• Editors: Cavaretta, Elena; Sande, Danny van de; Bouzas-Mosquera, Alberto; Simovic, Stefan; Thomson, Ross
• Is Part Of: European heart journal. Volume 5:Issue 2(2021)
• Publication Date: 2021-02-18
• Subjects: Case report -- Sepsis -- Cardiomyopathy -- Cardiac magnetic resonance imaging -- Computed tomography -- Transthoracic echocardiography; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytaa564
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: Diffuse myocardial calcification following severe sepsis is a rare complication whose long-term effects are not well-understood. Case summary: A 51-year-old man presented with a 6-month history of worsening dyspnoea on a background of sepsis 9 years prior. His initial echocardiogram showed moderate systolic dysfunction and a mildly dilated left ventricle. Cardiac computed tomography showed signs of mild coronary artery disease without significant stenosis, but the diffuse extensive left ventricular (LV) mid-myocardial calcification was visible. Cardiac magnetic resonance imaging showed diffuse extensive LV mid-myocardial late gadolinium enhancement in keeping with the calcification. He was diagnosed with non-ischaemic cardiomyopathy. He was commenced on appropriate anti-failure medical therapy, maintains New York Heart Association functional class II functional status, and has received a prophylactic implantable cardioverter-defibrillator. Discussion: Diffuse myocardial calcification might be associated with long-term development of non-ischaemic cardiomyopathy. The benefit of monitoring such patients for long-term effects is not routine, but should be considered.