Does Montelukast Have an Effect on Posttonsillectomy Pain Control in Children?. (2nd September 2014)

• Record Type: Journal Article
• Authors: Ince, Ilker; Yoruk, Ozgur; Ahıskalıoglu, Ali; Aksoy, Mehmet; Dostbil, Aysenur; Celik, Mine
• Is Part Of: Otolaryngology--head and neck surgery. Volume 151(2014)Supplement 1
• Page Start: P101
• Page End: P101
• Publication Date: 2014-09-02
• Subjects: Head -- Surgery -- Periodicals; Neck -- Surgery -- Periodicals; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1177/0194599814541627a228
• Languages: English
• ISSNs: 0194-5998

Abstract

Abstract : Objectives: Investigate the efficacy of preemptive montelukast, which is leukotreine receptor blocker for pediatric posttonsillectomy pain management. This is the first time montelucast has been used in posttonsillectomy pain control. Methods: A total of 60 children, aged 5 to 15 years, American Society of Anesthesiologist (ASA) class I‐II, scheduled for elective tonsillectomy were enrolled in this double‐blinded and controlled study from April of 2013 until January of 2014. The patients were randomized into 2 groups: Montelukast group (Group M, n:30) and control group (Group C, n:30). Group M received 5 mg oral montelukast tablet and Group C received placebo at 24:00 pm the night before surgery. The posttonsillectomy pain was evaluated with Wong‐Baker Face Scale during the 24 hours after surgery. Postoperative complications were recorded. The data were analyzed using the Student t test. Data were presented as a mean + SD, and differences were considered significant at P <. 05. Results: There were statistically significant differences between Wong‐Baker Face Scale scores of the Group C and Group M ( P <. 05). The first time, analgesic requirement was higher in group C than in group M ( P <. 05). There was no significant difference in demographic parameters and postoperative complications ( P >. 05 for both). Conclusions: Preemptive montelukast usage is more effective than the control group in posttonsillectomy pain relief.