Clinical Study of Carcinomas of the External Auditory Canal: Histologic and Treatment Groups. (2nd September 2014)

• Record Type: Journal Article
• Authors: Hosokawa, Seiji; Mizuta, Kunihiro; Takahashi, Goro; Okamura, Jun; Takizawa, Yoshinori; Hosokawa, Kumiko; Mineta, Hiroyuki
• Is Part Of: Otolaryngology--head and neck surgery. Volume 151(2014)Supplement 1
• Page Start: P159
• Page End: P159
• Publication Date: 2014-09-02
• Subjects: Head -- Surgery -- Periodicals; Neck -- Surgery -- Periodicals; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1177/0194599814541629a70
• Languages: English
• ISSNs: 0194-5998

Abstract

Abstract : Objectives: Evaluation of the clinical and pathological factors associated with treatment and outcomes for external auditory canal (EAC) carcinomas. Methods: Over the 20‐year period from 1993 to 2013, a retrospective review of clinical and pathological analysis was performed on 23 patients who were histologically diagnosed with EAC carcinomas and treated at Hamamatsu University Hospital. We evaluated the clinical staging, treatment methods, pathological diagnosis (particularly squamous cell carcinoma [SCC])), and patient outcomes. Main outcome measures included staging, treatment procedures, pathological features, and estimated survival rates. Results: The 5‐year overall survival (OS) of the subjects was 75.2%, and the 10‐year OS was 60.2% with the Kaplan‐Meier method. The prognosis for SCC was poor when compared with other carcinomas ( P =. 0462). The prognosis following treatment with surgery alone and following postoperative radiotherapy or chemoradiotherapy was significantly better than for the group of patients with unresectable tumors ( P =. 0004 and P =. 0001). There was no significant difference between the 4 tumor stage groups. Information on patients' survival status was obtained after a median follow‐up period of 57.5 months (range, 7‐151 months). Conclusions: Our survival analysis data for carcinoma of the EAC demonstrates that SCC and unresectable cases are associated with poor outcomes, and outcomes for subjects with operability more closely parallel the survival curves of advanced stage T4 disease. Patients with SCC should be strictly categorized as cases with severe disease.