Improvement in albuminuria in patients with type 2 diabetes after laparoscopic adjustable gastric banding. (November 2013)

• Record Type: Journal Article
• Authors: Stephenson, Dylan T; Jandeleit-Dahm, Karin; Balkau, Beverley; Cohen, Neale
• Is Part Of: Diabetes & vascular disease research. Volume 10:Number 6(2013)
• Page Start: 514
• Page End: 519
• Publication Date: 2013-11
• Subjects: Diabetes mellitus -- laparoscopic adjustable gastric banding -- microalbuminuria -- macroalbuminuria -- albumin–creatinine ratio -- obesity; Diabetic angiopathies -- Periodicals; 616.462005
• DOI: 10.1177/1479164113498083
• Languages: English
• ISSNs: 1479-1641

Abstract

Purpose: To determine the effects of laparoscopic adjustable gastric banding (LAGB) on albuminuria in patients with obesity, type 2 diabetes mellitus (T2DM) and established diabetic nephropathy. Methods: A retrospective analysis of clinical records from a tertiary diabetes service identified obese patients with T2DM who had micro- or macroalbuminuria prior to LAGB surgery. Clinical data from follow-up appointments including albuminuria were analysed. Results: A total of 23 T2DM patients were included in the final study. Of 7 patients with macroalbuminuria at baseline, 2 reverted to normoalbuminuria, 2 reverted to microalbuminuria and 3 remained with macroalbuminuria on their final recording in the 36-month period of follow-up. Of 16 patients with microalbuminuria, 9 reverted to normoalbuminuria, while 6 remained with microalbuminuria. Conclusion: This study demonstrates significant improvements in albuminuria in patients with established diabetic nephropathy following LAGB. These results suggest the potential for LAGB to improve or reverse renal damage in patients with T2DM.