Comparison between the difficulty of laparoscopic limited liver resections of tumors located in segment 7 versus segment 8: An international multicenter propensity‐score matched study. (20th July 2022)

• Record Type: Journal Article
• Authors: Efanov, Mikhail; Salimgereeva, Diana; Alikhanov, Ruslan; Wu, Andrew G. R.; Geller, David; Cipriani, Federica; Aghayan, Davit L.; Fretland, Asmund Avdem; Sijberden, Jasper; Belli, Andrea; Marino, Marco V.; Mazzaferro, Vincenzo; Chiow, Adrian K. H.; Sucandy, Iswanto; Ivanecz, Arpad; Choi, Sung Hoon; Lee, Jae Hoon; Prieto, Mikel; Vivarelli, Marco; Giuliante, Felice; Ruzzenente, Andrea; Yong, Chee‐Chien; Fondevila, Constantino; Rotellar, Fernando; Choi, Gi‐Hong; Robless Campos, Ricardo; Wang, Xiaoying; Sutcliffe, Robert P.; Pratschke, Johann; Lai, Eric; Chong, Charing C.; D'Hondt, Mathieu; Monden, Kazuteru; Lopez‐Ben, Santiago; Herman, Paulo; Di Benedetto, Fabrizio; Kingham, T. Peter; Liu, Rong; Long, Tran Cong duy; Ferrero, Alessandro; Levi Sandri, Giovanni Battista; Cherqui, Daniel; Scatton, Olivier; Wakabayashi, Go; Troisi, Roberto I.; Cheung, Tan‐To; Sugioka, Atsushi; Han, Ho‐Seong; Abu Hilal, Mohammad; Soubrane, Olivier; Fuks, David; Aldrighetti, Luca; Edwin, Bjorn; Goh, Brian K. P.;
• Other Names: Chan Chung‐Yip investigator.; Syn Nicholas investigator.; D'Silva Mizelle investigator.; Lee Boram investigator.; Lim Chetana investigator.; Nghia Phan Phuoc investigator.; Gastaca Mikel investigator.; Schotte Henri investigator.; De Meyere Celine investigator.; Krenzien Felix investigator.; Schmelzle Moritz investigator.; Lee Kit‐Fai investigator.; Lee Lip Seng investigator.; Jang Jae Young investigator.; Kojima Masayuki investigator.; Kato Yutaro investigator.; Ghotbi Jacob investigator.; Kruger Jaime Arthur Pirola investigator.; Coelho Fabricio Ferreira investigator.; Lopez‐Lopez Victor investigator.; Valle Bernardo Dalla investigator.; Robert Margarida Casellas I. investigator.; Mishima Kohei investigator.; Montalti Roberto investigator.; Giglio Mariano investigator.; Wang Hao‐Ping investigator.; Pascual Franco investigator.; Saleh Mansour investigator.; Kadam Prashant investigator.; Tang Chung‐Ngai investigator.; Ardito Francesco investigator.; Vani Simone investigator.; Giustizieri Ugo investigator.; Citterio Davide investigator.; Mocchegiani Federico investigator.; Ettorre Giuseppe Maria investigator.; Colasanti Marco investigator.; Guzmán Yoelimar investigator.; Dogeas Epameinondas investigator.; Magistri Paolo investigator.; Mazzotta Alessandro investigator.;
• Is Part Of: Journal of hepato-biliary-pancreatic sciences. Volume 30:Number 2(2023)
• Page Start: 177
• Page End: 191
• Publication Date: 2022-07-20
• Subjects: hepatectomy -- laparoscopy -- liver resection -- posterosuperior segments -- risk score; Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 617.556
• DOI: 10.1002/jhbp.1210
• Languages: English
• ISSNs: 1868-6974

Abstract

Abstract: Background: Presently, according to different difficulty scoring systems, there is no difference in complexity estimation of laparoscopic liver resection (LLR) of segments 7 and 8. However, there is no published data supporting this assumption. To date, no studies have compared the outcomes of laparoscopic parenchyma‐sparing resection of the liver segments 7 and 8. Methods: A post hoc analysis of patients undergoing LLR of segments 7 and 8 in 46 centers between 2004 and 2020 was performed. 1:1 Propensity score matching (PSM) was used to compare isolated LLR of segments 7 and 8. Subset analyses were also performed to compare atypical resections and segmentectomies of 7 and 8. Results: A total of 2411 patients were identified, and 1691 patients met the inclusion criteria. Comparison after PSM between the entire cohort of segment 7 and segment 8 resections revealed inferior results for segment 7 resection in terms of increased blood loss, blood transfusions, and conversions to open surgery. Subset analyses of only atypical resections similarly demonstrated poorer outcomes for segment 7 in terms of increased blood loss, operation time, blood transfusions, and conversions to open surgery. Conversely, a subgroup analysis of segmentectomies after PSM found better outcomes for segment 7 in terms of a shorter operation time and hospital stay. Conclusion: Differences in the outcomes of segments 7 and 8 resections suggest a greater difficulty of laparoscopic atypical resection of segment 7 compared to segment 8, and greater difficulty of segmentectomy 8 compared to segmentectomy 7.