Preoperative Chlorhexidine Showers Are Not Associated With a Reduction in Surgical Site Infection Following Craniotomy: An Examination of 3, 126 Surgeries. (16th November 2020)

• Record Type: Journal Article
• Authors: Ammanuel, Simon G; Edwards, Caleb S; Chan, Andrew K.H; Mummaneni, Praveen V; Kidane, Joseph; Vargas, Enrique; D'Souza, Sarah; Nichols, Amy D; Sankaran, Sujatha; Abla, Adib A; Aghi, Manish K; Chang, Edward F; Her vey-Jumper, Shawn L; Kunwar, Sandeep M; Larson, Paul S; Lawton, Michael T; Starr, Philip A; Theodosopoulos, Philip V; Berger, Mitchel S; McDermott, Michael W
• Is Part Of: Neurosurgery. Volume 67(2010)Supplement 1
• Publication Date: 2020-11-16
• Subjects: Nervous system -- Surgery -- Periodicals; 617.48005
• DOI: 10.1093/neuros/nyaa447_139
• Languages: English
• ISSNs: 0148-396X

Abstract

Abstract: INTRODUCTION: Surgical site infection (SSI) is a complication not commonly observed following craniotomy. Infections are not only associated with increased morbidity and mortality but are also incredibly burdensome to the healthcare system. METHODS: In November 2013, a preoperative CHG shower protocol was mandated at our institution. A total of 3, 126 surgeries were analyzed, encompassing a timeframe of April 2012 and April 2016. Cohorts before and after implementation of the CHG shower protocol were evaluated for differences in SSI rates. RESULTS: The overall SSI rate was 0.6%. No significant differences ( P = . 11) were observed between the rate of SSI in the 892 cases pre- (0.2%) and 2, 234 cases post-implementation (0.8%). Following multivariable analysis, the implementation of preoperative CHG showers was not associated with a decrease in SSI (adjusted odds ratio = 2.96 (95% CI: 0.67-13.1), P = . 15). CONCLUSION: This is the largest study, according to sample size, examining the effect of CHG showers on SSI following craniotomy. CHG showers did not significantly alter the risk of SSI after a cranial procedure.