Hemodynamic Evaluation of Intracranial Aneurysm: Comparison of Computational Fluid Dynamics with 4D Flow MRI. (16th November 2020)

• Record Type: Journal Article
• Authors: Misaki, Kouichi; Futami, Kazuya; Uno, Takehiro; Nambu, Iku; Yoshikawa, Akifumi; Kamide, Tomoya; Nakada, Mitsutoshi
• Is Part Of: Neurosurgery. Volume 67(2010)Supplement 1
• Publication Date: 2020-11-16
• Subjects: Nervous system -- Surgery -- Periodicals; 617.48005
• DOI: 10.1093/neuros/nyaa447_360
• Languages: English
• ISSNs: 0148-396X

Abstract

Abstract: INTRODUCTION: Although inflow hemodynamics of cerebral aneurysms may be a key factor of their rupture and recurrence after endovascular treatments, the most available method to evaluate inflow hemodynamics remains to be established. METHODS: In 23 unruptured cerebral aneurysms, the inflow hemodynamics was evaluated using both CFD and 4D flow MRI. Evaluated parameters included visually classified inflow jet patterns, the inflow rate ratio, i.e., the ratio of the inflow rate at the aneurysmal neck to the flow rate in the proximal parent artery, and the velocity ratio, i.e., the ratio of the inflow velocity to the velocity in the proximal parent artery. RESULTS: Inflow jet patterns were significantly correlated between 4D flow MRI and CFD ( P = . 008). There was a strong correlation between the Inflow rate ratio evaluated on 4D flow MRI and CFD (r = 0.770; P < . 001). Velocity ratio was moderately correlated between 4D flow MRI and CFD (r = 0.559; P = . 008). CONCLUSION: Inflow hemodynamics on CFD analysis and on 4D flow MRI imaging had good correlations in inflow jet pattern, inflow rate ratio and velocity ratio.