Durability of Immune Responses After Boosting in Ad26.COV2.S-Primed Healthcare Workers. (15th July 2022) - Sablerolles, Roos S G
Abstract: The emergence of SARS-CoV-2 variants raised questions regarding the durability of immune responses after homologous or heterologous boosters after Ad26.COV2.S-priming. We found that SARS-CoV-2–specific binding antibodies, neutralizing antibodies, and T cells are detectable 5 months after boosting, although waning of antibodies and limited cross-reactivity with Omicron BA.1 was observed.