Second trimester fetal MRI of the brain: Through the ground glass. Issue 2 (13th February 2023)

• Record Type: Journal Article
• Authors: Fileva, Nevena; Severino, Mariasavina; Tortora, Domenico; Ramaglia, Antonia; Paladini, Dario; Rossi, Andrea
• Other Names: Rizzo Giuseppe guestEditor.; Tonni Gabriele guestEditor.
• Is Part Of: Journal of clinical ultrasound. Volume 51:Issue 2(2023)
• Page Start: 283
• Page End: 299
• Publication Date: 2023-02-13
• Subjects: brain malformations -- cortical malformation -- fetal brain MRI -- posterior fossa; Ultrasonics in medicine -- Periodicals; 616.07543
• DOI: 10.1002/jcu.23423
• Languages: English
• ISSNs: 0091-2751

Abstract

Abstract: Fetal MRI is an important tool for the prenatal diagnosis of brain malformations and is often requested after second‐trimester ultrasonography reveals a possible abnormality. Despite the immature state of the fetal brain at this early stage, early suggestive signs of the presence of brain malformations can be recognized. To differentiate between the normal dynamics of the growing brain and the developing pathological conditions can be challenging and requires extensive knowledge of normal central nervous system developmental stages and their neuroradiological counterparts at those different stages. This article reviews the second‐trimester appearances of some commonly encountered brain malformations, focusing on helpful tricks and subtle signs to aid in the diagnosis of such conditions as rhombencephalosynapsis, various causes of vermian rotation, molar tooth spectrum anomalies, diencephalic‐mesencephalic junction dysplasia, ganglionic eminence anomalies, and the most common malformations of cortical development. Abstract : Fetal MRI is an important tool for the prenatal diagnosis of brain malformations and is often requested after second‐trimester ultrasonography reveals a possible abnormality. Despite the immature state of the fetal brain at this early stage, early suggestive signs of the presence of brain malformations can be recognized.