A "dual-key-and-lock" ratiometric fluorescent probe with biocompatibility and selectivity for imaging vicinal dithiol proteins. Issue 13 (25th January 2023)
- Record Type:
- Journal Article
- Title:
- A "dual-key-and-lock" ratiometric fluorescent probe with biocompatibility and selectivity for imaging vicinal dithiol proteins. Issue 13 (25th January 2023)
- Main Title:
- A "dual-key-and-lock" ratiometric fluorescent probe with biocompatibility and selectivity for imaging vicinal dithiol proteins
- Authors:
- Zou, Guang-Yue
Wen, Yun
Bi, Fan
Chen, Shuai
Yu, Yong-Liang
Wang, Jian-Hua - Abstract:
- Abstract : A ratiometric fluorescent probe based on a "dual-key-and-lock" design was reported for the imaging of vicinal dithiol proteins in living cells. Abstract : TMR-TPE, a ratiometric fluorescent probe, was reported for the imaging of vicinal dithiol proteins (VDPs) in living cells. Profiting from the "dual-key-and-lock" design, TMR-TPE solves the toxicity problem of VDP probes (98% cell viability at 50 μM) and avoids the interference of small thiols (up to 10 mM GSH). The change of VDPs during drug-induced liver injury was monitored for the first time using TMR-TPE.
- Is Part Of:
- Chemical communications. Volume 59:Issue 13(2023)
- Journal:
- Chemical communications
- Issue:
- Volume 59:Issue 13(2023)
- Issue Display:
- Volume 59, Issue 13 (2023)
- Year:
- 2023
- Volume:
- 59
- Issue:
- 13
- Issue Sort Value:
- 2023-0059-0013-0000
- Page Start:
- 1785
- Page End:
- 1788
- Publication Date:
- 2023-01-25
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d2cc06422g ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 25724.xml