The reconsolidation using rewind study (RETURN): trial protocol. Issue 1 (1st January 2021)

• Record Type: Journal Article
• Authors: Astill Wright, Laurence; Barawi, Kali; Simon, Natalie; Lewis, Catrin; Muss, David; Roberts, Neil P.; Kitchiner, Neil J; Bisson, Jonathan I
• Is Part Of: European journal of psychotraumatology. Volume 12:Issue 1(2021)
• Publication Date: 2021-01-01
• Subjects: PTSD -- RCT -- Rewind Technique -- Rewind Therapy -- protocol; TEPT -- ECA -- Técnica de Rebobinado -- Terapia de Rebobinado -- Protocolo; PTSD -- RCT -- Rewind技术 -- Rewind疗法方案; Post-traumatic stress disorder -- Periodicals; Stress Disorders, Post-Traumatic; Post-traumatic stress disorder; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; Periodicals; 616.8521
• DOI: 10.1080/20008198.2020.1844439
• Languages: English
• ISSNs: 2000-8198

Abstract

ABSTRACT: Background: An increasing body of research highlights reconsolidation-based therapies as emerging treatments for post-traumatic stress disorder (PTSD). The Rewind Technique is a non-pharmacological reconsolidation-based therapy with promising early results, which now requires evaluation through an RCT. Objectives: This is a preliminary efficacy RCT to determine if the Rewind Technique is likely to be a good candidate to test against usual care in a future pragmatic efficacy RCT. Methods: 40 participants will be randomised to receive either the Rewind Technique immediately, or after an 8 week wait. The primary outcome will be PTSD symptom severity as measured by the Clinician-Administered PTSD Scale for DSM5 (CAPS-5) at 8 and 16 weeks post-randomisation. Secondary outcome measures include the PTSD Checklist (PCL-5), International Trauma Questionnaire (ITQ), Patient Health Questionnaire (PHQ-9), the General Anxiety Disorder-7 (GAD-7), Insomnia Severity Index, the Euro-Qol-5D (EQ5D-5 L), the prominence of re-experiencing specific symptoms (CAPS-5) and an intervention acceptability questionnaire to measure tolerability of the intervention. Conclusions: This study will be the first RCT to assess the Rewind Technique. Using a cross-over methodology we hope to rigorously assess the efficacy and tolerability of Rewind using pragmatic inclusion criteria. Potential challenges include participant recruitment and retention. Trial registration: ISRCTN91345822 HIGHLIGHTS: This study will be the first RCT to rigorously assess the efficacy and tolerability of the Rewind Technique.