Biological active metabolites from microalgae for healthcare and pharmaceutical industries: A comprehensive review. (March 2023)

• Record Type: Journal Article
• Authors: Ibrahim, Tengku Nilam Baizura Tengku; Feisal, Nur Azalina Suzianti; Kamaludin, Noor Haziqah; Cheah, Wai Yan; How, Vivien; Bhatnagar, Amit; Ma, Zengling; Show, Pau Loke
• Is Part Of: Bioresource technology. Volume 372(2023)
• Publication Date: 2023-03
• Subjects: Biological active compounds -- Healthcare -- Metabolites -- Microalgae -- Pharmaceutical; Biomass -- Periodicals; Biomass energy -- Periodicals; Bioremediation -- Periodicals; Agricultural wastes -- Periodicals; Factory and trade waste -- Periodicals; Organic wastes -- Periodicals; Bioénergie -- Périodiques; Déchets agricoles -- Périodiques; Déchets industriels -- Périodiques; Déchets organiques -- Périodiques; Déchets (Combustible) -- Périodiques; 662.88
• DOI: 10.1016/j.biortech.2023.128661
• Languages: English
• ISSNs: 0960-8524

Abstract

Graphical abstract: Highlights: Microalgae have been exploited to produce healthcare and pharmaceutical products. Microalgae species that are capable to produce metabolites are summarised. Metabolites produced by microalgae were discussed with its benefits on health. Future prospects for microalgae application are proposed and discussed. Abstract: Microalgae are photoautotrophic microorganisms which comprise of species from several phyla. Microalgae are promising in producing a varieties of products, including food, feed supplements, chemicals, and biofuels. Medicinal supplements derived from microalgae are of a significant market in which compounds such as -carotene, astaxanthin, polyunsaturated fatty acids (PUFA) such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), and polysaccharides such as –glucan, are prominent. Microalgae species which are commonly applied for commercial productions include Isochrysis sp., Chaetoceros ( Chlorella sp.), Arthrospira sp. ( Spirulina Bioactive) and many more. In this present review, microalgae species which are feasible in metabolites production are being summarized. Metabolites produced by microalgae as well as their prospective applications in the healthcare and pharmaceutical industries, are comprehensively discussed. This evaluation is greatly assisting industrial stakeholders, investors, and researchers in making business decisions, investing in ventures, and moving the production of microalgae-based metabolites forward.